Article
The stable, functional core of DdrA from Deinococcus radiodurans R1 does not restore radioresistance in vivo.
Journal of bacteriology - 1 Oct 2008
Harris Dennis R, Ngo Khanh V, Cox Michael M
Abstract excerpt
DdrA protein binds to and protects 3' DNA ends and is essential for preserving the genome integrity of Deinococcus radiodurans following treatment by gamma radiation in an environment lacking nutrients. Limited proteolysis was used to identify a stable and functional protein core, designated DdrA157, consisting of the first 157 residues of the protein. In vitro, the biochemical differences between wild-type and...
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