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Article

Whole chromosome instability and cancer: a complex relationship.

Trends in genetics : TIG - 1 Sept 2008

Ricke Robin M, van Ree Janine H, van Deursen Jan M

Abstract excerpt

Although chromosome mis-segregation is a hallmark of cancer cells, its genetic basis and role in malignant transformation remain poorly understood. In recent years, several mouse models have been generated that harbor gene defects that perturb high-fidelity chromosome segregation. Analysis of the...

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Identifiers

PMID: 18675487
DOI: 10.1016/j.tig.2008.07.002
PMCID: PMC2594012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18675487-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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