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Article

Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis

1 Jan 2008

Abstract excerpt

BACKGROUND: To evaluate the impact of the duration of chronic inflammation on gene expression in skeletal muscle biopsies (MBx) from untreated children with juvenile dermatomyositis (JDM) and identify genes and biological processes associated with the disease progression, expression profiling data from 16 girls with active symptoms of JDM greater than or equal to 2 months were compared with 3 girls with active...

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PMID: 18671865
DOI: 10.1186/1471-2172-9-43

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