Article
Structure-function analysis of Knr4/Smi1, a newly member of intrinsically disordered proteins family, indispensable in the absence of a functional PKC1-SLT2 pathway in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 1 Aug 2008
Durand Fabien, Dagkessamanskaia Adilia, Martin-Yken Helene, Graille Marc, Van Tilbeurgh Herman, Uversky Vladimir N, François Jean M
Abstract excerpt
The coordination between cell wall synthesis and cell growth in the yeast Saccharomyces cerevisiae implicates the PKC1-dependent MAP kinase pathway. KNR4, encoding a 505 amino acid long protein, participates in this coordination, since it displays synthetic lethality with all the members of the PKC1 pathway and shows physical interaction with Slt2/Mpk1. The recent finding that KNR4 interacts genetically or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.