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The expression of cancer stem cell markers in human colorectal carcinoma cells in a microenvironment dependent manner

5 Feb 2017

Abstract excerpt

Numerous lines of evidence support the hierarchical model of cancer development and tumor initiation. According to the theory, cancer stem cells play a crucial role in the formation of the tumor and should be targeted for more effective anticancer treatment. However, cancer stem cells quickly loose their characteristics when propagated as 2D cell culture, indicating that the 2D cell culture does not provide the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28174005
DOI: 10.1016/j.bbrc.2017.01.111

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