Article
Association of genetic variations near P2 promoter of the hepatocyte nuclear factor-4alpha gene and insulin secretion index in Thais.
Acta diabetologica - 1 Dec 2007
Jongjaroenprasert W, Chanprasertyothin S, Kongsuksai A, Bunnag P, Puavilai G, Ongphiphadhanakul B
Abstract excerpt
This study was aimed to assess the association of the two single nucleotide polymorphisms (SNPs) near P2 promoter (rs1884614 and rs2144908) of hepatocyte nuclear factor-4alpha (HNF4A) with insulin secretion index and type 2 diabetes in Thais. Participants were categorized into three groups; unrelated type 2 diabetes (N = 219), prediabetes subjects (N = 228), and normal glucose tolerant controls (N = 203)....
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