Article
A support vector machine approach to assess drug efficacy of interferon-alpha and ribavirin combination therapy.
Molecular diagnosis & therapy - 1 Jan 2008
Lin Eugene, Hwang Yuchi
Abstract excerpt
BACKGROUND: Interferon-alpha (IFNalpha) in combination with ribavirin can be used for the treatment of patients with chronic hepatitis C. This therapeutic approach achieves an overall sustained response rate of approximately 40%, but treatment takes 6-12 months and patients often experience significant adverse reactions. OBJECTIVE: We aim to develop a tool to distinguish potential responders from nonresponders...
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