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Experimental and clinical progress of in utero hematopoietic cell transplantation therapy for congenital disorders

2 Sept 2022

Abstract excerpt

In utero hematopoietic cell transplantation (IUHCT) is considered a potentially efficient therapeutic approach with relatively few side effects, compared to adult hematopoietic cell transplantation, for various hematological genetic disorders. The principle of IUHCT has been extensively studied in rodent models and in some large animals with close evolutionary similarities to human beings. However, IUHCT has only...

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PMID: 36120324
DOI: 10.3389/fphar.2022.851375

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