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Article

TCF7L2 variants associate with CKD progression and renal function in population-based cohorts.

Journal of the American Society of Nephrology : JASN - 1 Oct 2008

Köttgen Anna, Hwang Shih-Jen, Rampersaud Evadnie, Coresh Josef, North Kari E, Pankow James S, Meigs James B, Florez Jose C, Parsa Afshin, Levy Daniel, Boerwinkle Eric, Shuldiner Alan R, Fox Caroline S, Kao W H Linda

Abstract excerpt

Genetic variants may increase susceptibility to both diabetes and kidney disease. Whether known diabetes-associated variants in the transcription factor 7-like 2 (TCF7L2) gene are associated with chronic kidney disease (CKD) progression and markers of kidney function is unknown. Participants of t...

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Identifiers

PMID: 18650481
DOI: 10.1681/ASN.2007121291
PMCID: PMC2551569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18650481-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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