Article
Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer.
International journal of cancer - 15 Oct 2008
Hwang Ki-Tae, Han Wonshik, Cho Jihyoung, Lee Jong Won, Ko Eunyoung, Kim Eun Kyu, Jung So-Youn, Jeong Eun-Mi, Bae Ji-Yeon, Kang Jason J, Yang Song-Ju, Kim Sung-Won, Noh Dong-Young
Abstract excerpt
We tried to establish models that predict systemic recurrence in breast cancer by selecting marker clones with DNA copy number alterations (CNAs) using an array comparative genomic hybridization (CGH). Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess CNAs in 62 primary breast cancer tissues from 31 patients with systemic recurrence within 5 years after surgery and...
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