Article
A new Bayesian automatic model selection approach for mapping quantitative trait loci under variance component model.
Genetica - 1 Apr 2009
Fang Ming, Jiang Dan, Gao Huijiang, Sun Dongxiao, Yang Runqing, Zhang Qin
Abstract excerpt
Bayesian variable selection implemented via reversible jump Markov chain Monte Carlo (RJMCMC) is an effective method for mapping multiple QTL. Recently, it has been used for QTL mapping both in inbred line crosses and in outbred populations. However, by RJMCMC, since the model-dimension is variable, the parameters are usually subject to poor mixing and difficult to converge. In inbred lines, the fixed effect...
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