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Article

Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p.

Biochemical and biophysical research communications - 3 Oct 2008

Williams Chris, van den Berg Marlene, Geers Erica, Distel Ben

Abstract excerpt

The Saccharomyces cerevisiae (Sc) PTS1 import receptor Pex5p is modified by ubiquitin, both in an Ubc4p-dependent and a Pex4p (Ubc10p)-dependent manner. Both of these modifications require the RING domain-containing protein Pex10p in vivo, but the actual role this protein plays in the ubiquitination of Pex5p has so far, remained enigmatic. Here, we report that the RING domain of Pex10p exhibits E(3) ligase...

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Identifiers

PMID: 18644345
DOI: 10.1016/j.bbrc.2008.07.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p.PMID 18644345Read ↗

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