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Article

The identification and characterization of a FOXL2 response element provides insights into the pathogenesis of mutant alleles.

Human molecular genetics - 15 Oct 2008

Benayoun Bérénice A, Caburet Sandrine, Dipietromaria Aurélie, Bailly-Bechet Marc, Batista Frank, Fellous Marc, Vaiman Daniel, Veitia Reiner A

Abstract excerpt

The Forkhead transcription factor FOXL2 plays a crucial role in ovarian development and maintenance. In humans, its mutations lead to craniofacial abnormalities, isolated or associated with ovarian dysfunction. Using a combinatorial approach, we identified and characterized a FoxL2 response eleme...

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Share to Forkhead Box Protein L2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18635577
DOI: 10.1093/hmg/ddn209

Genes

FOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18635577-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The identification and characterization of a FOXL2 response element provides insights into the pathogenesis of mutant alleles.PMID 18635577Read ↗

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Mutational probing of the forkhead domain of the transcription factor FOXL2 provides insights into the pathogenicity of naturally occurring mutations.Semantic proximity Read ↗

Shifting the landscape: Dominant C-terminal rare missense FOXL2 variants in non-syndromic primary ovarian failure etiology.Semantic proximity Read ↗

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