Article
The mutations and potential targets of the forkhead transcription factor FOXL2.
Molecular and cellular endocrinology - 30 Jan 2008
Moumné L, Batista F, Benayoun B A, Nallathambi J, Fellous M, Sundaresan P, Veitia R A
Abstract excerpt
Mutations of FOXL2, a gene encoding a forkhead transcription factor, have been shown to cause the blepharophimosis-ptosis-epicanthus inversus syndrome (BPES). This genetic disorder is characterized by eyelid and mild craniofacial abnormalities that can appear associated with premature ovarian failure. FOXL2 is one of the earliest ovarian markers and it offers, along with its targets, an excellent model to study...
Topics
Join the communities discussing this publication.