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Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics

21 Feb 2007

Abstract excerpt

FOXL2 is a gene encoding a forkhead transcription factor, whose mutations are responsible for the blepharophimosis-ptosis-epicanthus inversus syndrome that often involves premature ovarian failure. FOXL2 is one of the earliest ovarian markers and it offers, along with its targets, an excellent model to study ovarian development and function in normal and pathological conditions. We have recently shown that the...

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PMID: 17360647
DOI: 10.1073/pnas.0611326104

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