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Article

Shorter telomeres may indicate dementia status in older individuals with Down syndrome.

Neurobiology of aging - 1 May 2010

Jenkins Edmund C, Ye Lingling, Gu Hong, Ni Samantha A, Velinov Milen, Pang Deborah, Krinsky-McHale Sharon J, Zigman Warren B, Schupf Nicole, Silverman Wayne P

Abstract excerpt

We have recently reported reduced telomere length in T lymphocytes of individuals with Down syndrome (DS) and dementia due to Alzheimer's disease (AD). We have now replicated and extended that study by finding that people with DS and mild cognitive impairment (MCI-DS) also have shorter telomeres...

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Identifiers

PMID: 18635289
DOI: 10.1016/j.neurobiolaging.2008.06.001
PMCID: PMC2842474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18635289-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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