Article
Shorter telomeres may indicate dementia status in older individuals with Down syndrome.
Neurobiology of aging - 1 May 2010
Jenkins Edmund C, Ye Lingling, Gu Hong, Ni Samantha A, Velinov Milen, Pang Deborah, Krinsky-McHale Sharon J, Zigman Warren B, Schupf Nicole, Silverman Wayne P
Abstract excerpt
We have recently reported reduced telomere length in T lymphocytes of individuals with Down syndrome (DS) and dementia due to Alzheimer's disease (AD). We have now replicated and extended that study by finding that people with DS and mild cognitive impairment (MCI-DS) also have shorter telomeres than people with DS without MCI-DS. Additional new findings demonstrated that light intensity measurements from...
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