Article
Chromosome 5q deletion: specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution.
Leukemia research - 1 Mar 2008
Santana-Davila Rafael, Holtan Shernan G, Dewald Gordon W, Ketterling Rhett P, Knudson Ryan A, Hanson Curtis A, Steensma David P, Tefferi Ayalew
Abstract excerpt
The purpose of this study was to define the spectrum of hematologic neoplasms and chromosomal breakpoints associated with del(5q); separate analyses were performed to account for prior cytotoxic treatment. A total of 358 consecutive del(5q) cases were identified; specific diagnoses included myelodysplastic syndrome (MDS; 53%), acute myeloid leukemia (AML; 22%), plasma cell proliferative disorder (PCPD; 9%),...
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