Article
Flow cytometric phenotype of rhabdomyosarcoma bone marrow metastatic cells and its implication in differential diagnosis with neuroblastoma.
Anticancer research - 1 Jan 2000
Bozzi Fabio, Collini Paola, Aiello Antonella, Barzanò Elena, Gambirasio Felicita, Podda Marta, Meazza Cristina, Ferrari Andrea, Luksch Roberto
Abstract excerpt
BACKGROUND: The goal of this study was to develop a flow cytometric (FCM) method for assessing the presence of metastatic cells in bone marrow (BM) and peripheral blood (PB) obtained from rhabdomysarcoma (RMS) patients. Myogenin (Myf4), a specific molecular RMS marker, was also investigated in the same samples. Since neuroblastoma (NB) metastasizes to the BM, the potential application of cytometry in differential...
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