Article
Detection of residual neuroblastoma cells in bone marrow: comparison of flow cytometry with immunocytochemistry.
Cytometry. Part B, Clinical cytometry - 1 Sept 2004
Swerts Katrien, De Moerloose Barbara, Dhooge Catharina, Brichard Bénédicte, Benoit Yves, Laureys Geneviève, Philippé Jan
Abstract excerpt
BACKGROUND: Because the cytomorphologic examination of bone marrow (BM) aspirates appears not sensitive enough to detect residual neuroblastoma cells, two four-color flow cytometric assays using different combinations of CD9, CD81, CD56, CD45, and anti-GD2 were evaluated. METHODS: The sensitivity of the flow cytometric assays was assessed by spiking experiments in normal peripheral blood samples. Twenty-eight BM...
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