Article
Reduced folate carrier 80A-->G polymorphism, plasma folate, and risk of placental abruption.
Human genetics - 1 Sept 2008
Ananth Cande V, Peltier Morgan R, Moore Dirk F, Kinzler Wendy L, Leclerc Daniel, Rozen Rima R
Abstract excerpt
Folate deficiency and maternal smoking are strong risk factors for placental abruption. We assessed whether the reduced folate carrier [NM_194255.1: c.80A-->G (i.e., p.His27Arg)] (RFC-1) polymorphism was associated with placental abruption, and evaluated if maternal smoking modified the association between plasma folate and abruption. Data were derived from the New Jersey-Placental Abruption Study--a multicenter,...
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