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Article

Associations between 2 polymorphisms in the methylenetetrahydrofolate reductase gene and placental abruption.

American journal of obstetrics and gynecology - 1 Oct 2007

Ananth Cande V, Peltier Morgan R, De Marco Celeste, Elsasser Denise A, Getahun Darios, Rozen Rima, Smulian John C

Abstract excerpt

OBJECTIVE: Heritable thrombophilias have been implicated as a potential cause of abruption by vascular disruption at the uteroplacental interface. Polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene have been linked to vascular complications outside of pregnancy, which includes stroke. Given the underlying thrombotic nature of abruption, we hypothesized that polymorphisms in the MTHFR gene are...

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Source

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Identifiers

PMID: 17904970
DOI: 10.1016/j.ajog.2007.06.046
PMCID: PMC2084064

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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