Article
PcaO positively regulates pcaHG of the beta-ketoadipate pathway in Corynebacterium glutamicum.
Journal of bacteriology - 1 Mar 2010
Zhao Ke-Xin, Huang Yan, Chen Xi, Wang Nan-Xi, Liu Shuang-Jiang
Abstract excerpt
We identified a new regulator, PcaO, which is involved in regulation of the protocatechuate (PCA) branch of the beta-ketoadipate pathway in Corynebacterium glutamicum. PcaO is an atypical large ATP-binding LuxR family (LAL)-type regulator and does not have a Walker A motif. A mutant of C. glutamicum in which pcaO was disrupted (RES167DeltapcaO) was unable to grow on PCA, and growth on PCA was restored by...
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