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Article

PcaO positively regulates pcaHG of the beta-ketoadipate pathway in Corynebacterium glutamicum.

Journal of bacteriology - 1 Mar 2010

Zhao Ke-Xin, Huang Yan, Chen Xi, Wang Nan-Xi, Liu Shuang-Jiang

Abstract excerpt

We identified a new regulator, PcaO, which is involved in regulation of the protocatechuate (PCA) branch of the beta-ketoadipate pathway in Corynebacterium glutamicum. PcaO is an atypical large ATP-binding LuxR family (LAL)-type regulator and does not have a Walker A motif. A mutant of C. glutamicum in which pcaO was disrupted (RES167DeltapcaO) was unable to grow on PCA, and growth on PCA was restored by...

Topics

Adipates
Bacterial Proteins
Corynebacterium glutamicum
Culture Media
Gene Expression Regulation, Bacterial
Hydroxybenzoates
Mutation
Promoter Regions, Genetic
Time Factors
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20081038
DOI: 10.1128/JB.01338-09
PMCID: PMC2832523

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