Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis.

International journal of antimicrobial agents - 1 Sept 2008

Biswas Silpak, Raoult Didier, Rolain Jean-Marc

Abstract excerpt

Intracellular bacteria survive within eukaryotic host cells and are difficult to kill with certain antibiotics. As a result, antibiotic resistance in intracellular bacteria is becoming commonplace in healthcare institutions. Owing to the lack of methods available for transforming these bacteria, we evaluated the mechanisms of resistance using molecular methods and in silico genome analysis. The objective of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteria
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoplasm

Share to Drug Resistance, Bacterial

Share to Genome, Bacterial

Share to Microbial Sensitivity Tests

Share to Phagosomes

Share to RNA, Ribosomal, 23S

Source

Identifiers

PMID: 18619818
DOI: 10.1016/j.ijantimicag.2008.03.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis.PMID 18619818Read ↗

The Bacterial Genomic Context of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases Highlights an Emerging Threat to Public HealthSemantic proximity Read ↗

Antimicrobial resistance gene lack in tick-borne pathogenic bacteriaSemantic proximity Read ↗

Evolution toward high-level fluoroquinolone resistance in Francisella speciesSemantic proximity Read ↗

Functional Characterization of the DNA Gyrases in Fluoroquinolone-Resistant Mutants of Francisella novicida.Semantic proximity Read ↗

Phenotypic and genetic characterization of macrolide resistance in Francisella tularensis subsp. holarctica biovar I.Semantic proximity Read ↗

Mycobacterium abscessus Genetic Determinants Associated with the Intrinsic Resistance to AntibioticsSemantic proximity Read ↗

Subtractive Genomic Analysis for Identification of Novel Drug Targets and Vaccine Candidates against <i>Bartonella bacilliformis</i> subsp. Ver097Semantic proximity Read ↗

Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis.Semantic proximity Read ↗

The complete genome sequence of Francisella tularensis, the causative agent of tularemia.Semantic proximity Read ↗

Whole genome sequencing of the fish pathogen Francisella noatunensis subsp. orientalis Toba04 gives novel insights into Francisella evolution and pathogenecity.Semantic proximity Read ↗

Integron-Associated DfrB4, a Previously Uncharacterized Member of the Trimethoprim-Resistant Dihydrofolate Reductase B Family, Is a Clinically Identified Emergent Source of Antibiotic ResistanceSemantic proximity Read ↗

Chlamydia trachomatis clinical isolates identified as tetracycline resistant do not exhibit resistance in vitro: whole-genome sequencing reveals a mutation in porB but no evidence for tetracycline resistance genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.