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Article

Phenotypic and genetic characterization of macrolide resistance in Francisella tularensis subsp. holarctica biovar I.

The Journal of antimicrobial chemotherapy - 1 Nov 2010

Gestin Brieuc, Valade Eric, Thibault François, Schneider Dominique, Maurin Max

Abstract excerpt

OBJECTIVES: Francisella tularensis subsp. holarctica strains are classified as biovars I and II, which are susceptible and naturally resistant to the macrolide erythromycin, respectively. The present study was aimed at both selecting biovar I strains with increased levels of erythromycin resistance and characterizing the underlying genetic mechanisms. METHODS: Serial cultures in the presence of increasingly high...

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PMID: 20837574
DOI: 10.1093/jac/dkq315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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