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Article

Behavioral phenotypic variation in autism multiplex families: evidence for a continuous severity gradient.

American journal of medical genetics - 8 Mar 2002

Spiker Donna, Lotspeich Linda J, Dimiceli Sue, Myers Richard M, Risch Neil

Abstract excerpt

Recent genetic investigations of autism have studied multiplex families, typically including families with multiple siblings who meet criteria for a diagnosis of autism. However, little is known about the specific behavioral characteristics of siblings with autism in these multiplex families. We investigated the behavioral phenotypic variability and similarity of 351 siblings with autism in 171 multiplex families...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11857572
DOI: 10.1002/ajmg.10188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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