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Article

The yeast glutaredoxins are active as glutathione peroxidases.

The Journal of biological chemistry - 10 May 2002

Collinson Emma J, Wheeler Glen L, Garrido Ester Ocón, Avery Angela M, Avery Simon V, Grant Chris M

Abstract excerpt

The yeast Saccharomyces cerevisiae contains two glutaredoxins, encoded by GRX1 and GRX2, which are active as glutathione-dependent oxidoreductases. Our studies show that changes in the levels of glutaredoxins affect the resistance of yeast cells to oxidative stress induced by hydroperoxides. Elevating the gene dosage of GRX1 or GRX2 increases resistance to hydroperoxides including hydrogen peroxide, tert-butyl...

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Source

Identifiers

PMID: 11875065
DOI: 10.1074/jbc.M111686200

Genes

GPX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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