Article
Vascular endothelial growth factor polymorphisms -1154 G/A and -460 C/T are not associated with VEGF mRNA expression and susceptibility to sporadic colon cancer.
DNA and cell biology - 1 Oct 2008
Cacev Tamara, Loncar Bozo, Seiwerth Sven, Spaventi Sime, Kapitanovic Sanja
Abstract excerpt
Vascular endothelial growth factor (VEGF) is important mediator of angiogenesis, and its expression in colorectal tumors is related to tumor progression. VEGF expression has been detected in normal mucosa, primary colon cancers, and metastatic tumors, and patients with low VEGF expression have a...
Topics
- 5' Untranslated Regions
- Aged
- Case-Control Studies
- Colonic Neoplasms
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- RNA, Messenger
- RNA, Neoplasm
- Reverse Transcriptase Polymerase Chain Reaction
- Vascular Endothelial Growth Factor A