Article
Practical considerations for dividing data into subsets prior to PPL analysis.
Human heredity - 1 Jan 2008
Govil M, Vieland V J
Abstract excerpt
OBJECTIVE: The PPL, a class of statistics for complex trait genetic mapping in humans, utilizes Bayesian sequential updating to accumulate evidence for or against linkage across potentially heterogeneous data (sub)sets. Here, we systematically explore the relative efficacy of alternative subsetting approaches for purposes of PPL calculation. METHODS: We simulated genotypes for three pedigree sets (sib pairs; 2-3...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.