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Article

Effect of formal statistical significance on the credibility of observational associations.

American journal of epidemiology - 15 Aug 2008

Ioannidis John P A

Abstract excerpt

The author evaluated the implications of nominal statistical significance for changing the credibility of null versus alternative hypotheses across a large number of observational associations for which formal statistical significance (p < 0.05) was claimed. Calculation of the Bayes factor (B) under different assumptions was performed on 272 observational associations published in 2004-2005 and a data set of 50...

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Identifiers

PMID: 18611956
DOI: 10.1093/aje/kwn156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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