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Article

Phenotypic changes of methicillin-resistant Staphylococcus aureus during vancomycin therapy for persistent bacteraemia and related clinical outcome.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Aug 2017

Kim T, Kim E S, Park S Y, Sung H, Kim M-N, Kim S-H, Lee S-O, Choi S-H, Jeong J-Y, Woo J H, Chong Y P, Kim Y S

Abstract excerpt

Persistent bacteraemia (PB) due to methicillin-resistant Staphylococcus aureus (MRSA) that fails to respond to glycopeptide therapy is a well-documented clinical problem. There are limited data on changes in agr functionality, vancomycin susceptibility and heteroresistance during MRSA PB. Thus, the frequency of these changes and their clinical significance remain unclear. Only patients with MRSA PB (≥7 days) from...

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PMID: 28337607
DOI: 10.1007/s10096-017-2956-1

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