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Article

In inclusion-body myositis muscle fibers Parkinson-associated DJ-1 is increased and oxidized.

Free radical biology & medicine - 15 Sept 2008

Terracciano Chiara, Nogalska Anna, Engel W King, Wojcik Slawomir, Askanas Valerie

Abstract excerpt

Sporadic inclusion-body myositis (s-IBM) is the most common muscle disease of older persons. The muscle-fiber molecular phenotype exhibits similarities to both Alzheimer-disease (AD) and Parkinson-disease (PD) brains, including accumulations of amyloid-beta, phosphorylated tau, alpha-synuclein, and parkin, as well as evidence of oxidative stress and mitochondrial abnormalities. Early-onset autosomal-recessive PD...

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Share to Intracellular Signaling Peptides and Proteins
Share to Muscle Fibers, Skeletal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oncogene Proteins

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Source

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Identifiers

PMID: 18601999
DOI: 10.1016/j.freeradbiomed.2008.05.030
PMCID: PMC2579266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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