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Article

Molecular pathology and pathogenesis of inclusion-body myositis.

Microscopy research and technique - 1 Jul 2005

Askanas Valerie, Engel W King

Abstract excerpt

We summarize the molecular phenotype, diagnostic criteria, and the newest advances related to seeking the pathogenic mechanism(s) of sporadic inclusion-body myositis (s-IBM), a muscle disease usually of persons over age 50. On the basis of our research, several processes seem to be important in relation to the still-speculative pathogenesis: 1) increased transcription and accumulation of amyloid-beta precursor...

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Identifiers

PMID: 16104000
DOI: 10.1002/jemt.20186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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