Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The cyclic AMP phenotype of fragile X and autism.

Neuroscience and biobehavioral reviews - 1 Oct 2008

Kelley Daniel J, Bhattacharyya Anita, Lahvis Garet P, Yin Jerry C P, Malter Jim, Davidson Richard J

Abstract excerpt

Cyclic AMP (cAMP) is a second messenger involved in many processes including mnemonic processing and anxiety. Memory deficits and anxiety are noted in the phenotype of fragile X (FX), the most common heritable cause of mental retardation and autism. Here we review reported observations of altered cAMP cascade function in FX and autism. Cyclic AMP is a potentially useful biochemical marker to distinguish autism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to Autistic Disorder
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

Share to Fragile X Syndrome

Share to Memory

Share to Models, Biological

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 18601949
DOI: 10.1016/j.neubiorev.2008.06.005
PMCID: PMC2642647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The cyclic AMP phenotype of fragile X and autism.PMID 18601949Read ↗

Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila.Semantic proximity Read ↗

Autism spectrum disorder in the fragile X premutation state: possible mechanisms and implications.Semantic proximity Read ↗

Neuropsychiatric symptoms of fragile X syndrome: pathophysiology and pharmacotherapy.Semantic proximity Read ↗

Role of the endocannabinoid system in fragile X syndrome: potential mechanisms for benefit from cannabidiol treatmentSemantic proximity Read ↗

Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortexSemantic proximity Read ↗

Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndromeSemantic proximity Read ↗

Autism profiles of males with fragile X syndrome.Semantic proximity Read ↗

Melatonin as an Interventional Novel Candidate for the Individual with Autistic Fragile X Syndrome in HumanSemantic proximity Read ↗

Reduced cyclic AMP production in fragile X syndrome: cytogenetic and molecular correlations.Semantic proximity Read ↗

The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome.Semantic proximity Read ↗

Abnormal GABA-mediated and cerebellar inhibition in women with the fragile X premutation.Semantic proximity Read ↗

Cardiac autonomic regulation in autism and Fragile X syndrome: A review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.