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Article

Evidence for a pseudo-autosomal locus for schizophrenia using the method of affected sibling pairs.

The British journal of psychiatry : the journal of mental science - 1 May 1991

Collinge J, Delisi L E, Boccio A, Johnstone E C, Lane A, Larkin C, Leach M, Lofthouse R, Owen F, Poulter M

Abstract excerpt

A susceptibility locus for schizophrenia in the 'pseudo-autosomal' region has been proposed on the basis of the reported excess of sex-chromosome aneuploidies (e.g. XXY and XXX) among patients with schizophrenia and the finding that schizophrenic sib-pairs are more often of the same than of the opposite sex. This hypothesis has been tested in 83 sibships with two or more siblings fulfilling Research Diagnostic...

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Identifiers

PMID: 1860017
DOI: 10.1192/bjp.158.5.624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for a pseudo-autosomal locus for schizophrenia using the method of affected sibling pairs.PMID 1860017Read ↗

Evidence for a pseudoautosomal locus for schizophrenia. II: Replication of a non-random segregation of alleles at the DXYS14 locus.Semantic proximity Read ↗

No evidence for a pseudoautosomal locus for schizophrenia. Linkage analysis of multiply affected families.Semantic proximity Read ↗

Pseudoautosomal locus for schizophrenia excluded in 12 pedigrees.Semantic proximity Read ↗

An examination of linkage of schizophrenia and schizoaffective disorder to the pseudoautosomal region (Xp22.3)Semantic proximity Read ↗

Evidence for a pseudoautosomal locus for schizophrenia. I: A replication study using phenotype analysis.Semantic proximity Read ↗

Analysis of the pseudoautosomal X-linked gene SYBL1in bipolar affective disorder: description of a new candidate allele for psychiatric disorders.Semantic proximity Read ↗

Lack of linkage between schizophrenia and markers at the telomeric end of the pseudoautosomal region of the sex chromosomes.Semantic proximity Read ↗

Allele sharing for schizophrenia and schizo-affective disorder within a region of Homo sapiens specific XY homology.Semantic proximity Read ↗

Failure to establish linkage on the X chromosome in 301 families with schizophrenia or schizoaffective disorder.Semantic proximity Read ↗

A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.Semantic proximity Read ↗

Male siblings with schizophrenia share alleles at the androgen receptor above chance expectation.Semantic proximity Read ↗

Pseudolinkage of the duplicate loci for supernatant aspartate aminotransferase in brook trout, Salvelinus fontinalis.Semantic proximity Read ↗

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