Article
Pseudoautosomal locus for schizophrenia excluded in 12 pedigrees.
Archives of general psychiatry - 1 Mar 1993
Wang Z W, Black D, Andreasen N, Crowe R R
Abstract excerpt
A pseudoautosomal locus for schizophrenia has been proposed based on observations of an excess of same-sex affected sibling pairs over opposite-sex pairs when the transmitting parent is the father. Such a pattern of partial concordance by sex related to paternal transmission would be difficult to explain by any biologic mechanism other than pseudoautosomal transmission of schizophrenia. To test the...
Topics
- Chromosome Mapping
- Family
- Female
- Genetic Linkage
- Humans
- Lod Score
- Male
- Models, Genetic
- Pedigree
- Phenotype
- Schizophrenia
- Sex Chromosomes
