Article
Curcumin blocks RON tyrosine kinase-mediated invasion of breast carcinoma cells.
Cancer research - 1 Jul 2008
Narasimhan Madhusudhanan, Ammanamanchi Sudhakar
Abstract excerpt
We have recently shown that macrophage-stimulating protein (MSP) promotes the invasion of recepteur d'origine nantais (RON), a tyrosine kinase receptor-positive MDA-MB-231, MDA-MB-468 breast cancer cells, and also identified the regulatory elements required for RON gene expression. In this report, we have analyzed the efficacy of a chemopreventive agent, curcumin, in blocking RON tyrosine kinase-mediated invasion...
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