Article
One of the hottest topics in epileptology: ABC proteins. Their inhibition may be the future for patients with intractable seizures.
Neurological research - 1 Nov 2008
Hughes John R
Abstract excerpt
One of the new topics in epileptology is the ABC proteins, which seem to control whether or not anti-epileptic drugs (AEDs) can come in contact with and affect the epileptogenic areas that cause seizures. The goal of this report is to simplify the concepts involved in these proteins and then to review the progress made in the field, especially of one protein called P-glycoprotein (P-gp). First, the ABC proteins...
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