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Article

Prostasin: a possible candidate gene for human hypertension.

American journal of hypertension - 1 Sept 2008

Zhu Haidong, Guo Dehuang, Li Ke, Yan Weili, Tan Yuande, Wang Xiaoling, Treiber Frank A, Chao Julie, Snieder Harold, Dong Yanbin

Abstract excerpt

BACKGROUND: Prostasin, a serine protease, is suggested to be a novel mechanism regulating the epithelial sodium channel (ENaC) expressed in the distal nephron. This study aimed to evaluate whether the human prostasin gene is a novel candidate gene underlying blood pressure (BP) elevation. METHODS: In a sample of healthy African-American (AA) and European-American (EA) twin subjects aged 17.6 +/- 3.3 years (n =...

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Source

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Identifiers

PMID: 18583984
DOI: 10.1038/ajh.2008.224
PMCID: PMC3812941

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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