Discrimination learning in Rora(sg) and Grid2(ho) mutant mice.

doi:10.1016/j.nlm.2008.05.004

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Article

Discrimination learning in Rora(sg) and Grid2(ho) mutant mice.

Neurobiology of learning and memory - 1 Sept 2008

Lalonde R, Strazielle C

Abstract excerpt

Rora(sg) mutants with mild cerebellar granule cell degeneration were compared to Grid2(ho) mutants with more severe granule cell degeneration as well as Purkinle cell atrophy for left-right and dark-light discrimination learning tasks in a water-filled T-maze. The acquisition rate of both cerebellar mutants was slowed down during light-dark but not left-right discrimination learning. However, the mutants were...

Topics

Adaptor Proteins, Signal Transducing
Alleles
Animals
Atrophy
Avoidance Learning
Cerebellar Cortex
Discrimination Learning
Escape Reaction
Fear
Maze Learning
Mental Recall
Mice
Mice, Inbred C57BL
Mice, Neurologic Mutants
Motivation
Neurons
Nuclear Receptor Subfamily 1, Group F, Member 1
Orientation

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Open in PubMed

Identifiers

PMID: 18583162
DOI: 10.1016/j.nlm.2008.05.004

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