Article
Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression.
Molecular biology of the cell - 1 Sept 2008
Turner David P, Findlay Victoria J, Kirven A Darby, Moussa Omar, Watson Dennis K
Abstract excerpt
Prostate derived ETS factor (PDEF) is an ETS (epithelial-specific E26 transforming sequence) family member that has been identified as a potential tumor suppressor. In multiple invasive breast cancer cells, PDEF expression inhibits cell migration by preventing the acquisition of directional morph...
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