Article
HLA-B*27/HLA-B*07 in combination with D6S273-134 allele is associated with increased susceptibility to juvenile spondyloarthropathies.
Clinical and experimental rheumatology - 1 Jan 2000
Harjacek M, Margetić T, Kerhin-Brkljacić V, Martinez N, Grubić Z
Abstract excerpt
OBJECTIVE: Juvenile spondylarthropathies (jSpA) are polygenic and the clustering of disease in families is caused mainly by genetic factors. Our aim was to look for possible associations of other HLA-A and B specificities, MICA and D6S273 microsatellite polymorphisms that might play a role in determining the susceptibility to jSpA. PATIENTS AND METHODS: jSpA were diagnosed in 74 Croatian children, and 169 healthy...
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