Article
Genetic polymorphisms in the Renin-Angiotensin system in high-altitude and low-altitude Native American populations.
Annals of human genetics - 1 Jan 2003
Rupert J L, Kidd K K, Norman L E, Monsalve M V, Hochachka P W, Devine D V
Abstract excerpt
Cardiovascular disease (CVD) is reportedly less common in high-altitude native populations than in lowlanders. To some extent, this is due to cultural and demographic factors; however, increased cardiovascular efficiency contributing to hypoxia adaptation may also be involved. Numerous genetic variants have been associated with cardiovascular health. If the decreased incidence of CVD in modern high-altitude...
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