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Article

Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae.

PloS one - 1 Jan 2014

Mitchell Sara N, Rigden Daniel J, Dowd Andrew J, Lu Fang, Wilding Craig S, Weetman David, Dadzie Samuel, Jenkins Adam M, Regna Kimberly, Boko Pelagie, Djogbenou Luc, Muskavitch Marc A T, Ranson Hilary, Paine Mark J I, Mayans Olga, Donnelly Martin J

Abstract excerpt

The development of resistance to insecticides has become a classic exemplar of evolution occurring within human time scales. In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of both target-site resistance mechanisms that have int...

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Identifiers

PMID: 24675797
DOI: 10.1371/journal.pone.0092662
PMCID: PMC3968025

Genes

DDT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24675797-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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