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Article

CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

PLoS genetics - 1 Mar 2014

Edi Constant V, Djogbénou Luc, Jenkins Adam M, Regna Kimberly, Muskavitch Marc A T, Poupardin Rodolphe, Jones Christopher M, Essandoh John, Kétoh Guillaume K, Paine Mark J I, Koudou Benjamin G, Donnelly Martin J, Ranson Hilary, Weetman David

Abstract excerpt

Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative insecticides is advocated for indoor residual spraying (IRS), and carbamates are increasingly important. Emergence of a very strong carbamate resistance phenotype in Anopheles gambiae from Tiassalé, Côte d'Ivoire, West Africa, is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24651294
DOI: 10.1371/journal.pgen.1004236
PMCID: PMC3961184

Genes

ACE
DDT

Variants

Provenance

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