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Simultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE

21 May 2008

Abstract excerpt

BACKGROUND: Leishmania (L) are intracellular protozoan parasites that are able to survive and replicate within the harsh and potentially hostile phagolysosomal environment of mammalian mononuclear phagocytes. A complex interplay then takes place between the macrophage (MPhi) striving to eliminate the pathogen and the parasite struggling for its own survival. To investigate this host-parasite conflict at the...

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PMID: 18495030
DOI: 10.1186/1471-2164-9-238

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