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Cerebral Mitochondrial Metabolism in Early Parkinson's Disease

25 Jun 2008

Abstract excerpt

Abnormal cerebral energy metabolism owing to dysfunction of mitochondrial electron transport has been implicated in the pathogenesis of Parkinson's disease (PD). However, in vivo data of mitochondrial dysfunction have been inconsistent. We directly investigated mitochondrial oxidative metabolism in vivo in 12 patients with early, never-medicated PD and 12 age-matched normal controls by combined measurements of...

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PMID: 18575458
DOI: 10.1038/jcbfm.2008.63

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