Article
Induction of chondrogenic phenotype in synovium-derived progenitor cells by intermittent hydrostatic pressure.
Osteoarthritis and cartilage - 1 Jul 2008
Sakao K, Takahashi K A, Arai Y, Inoue A, Tonomura H, Saito M, Yamamoto T, Kanamura N, Imanishi J, Mazda O, Kubo T
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the effect of intermittent hydrostatic pressure (IHP) on chondrogenic differentiation of synovium-derived progenitor cells (SPCs). METHODS: SPCs, bone marrow-derived progenitor cells and skin fibroblasts from rabbits were subjected to IHP ranging from 1.0 to 5.0 MPa. The mRNA expression of proteoglycan core protein (PG), collagen type II and SOX-9 was examined...
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