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Article

Hydrostatic pressure acts to stabilise a chondrogenic phenotype in porcine joint tissue derived stem cells.

European cells & materials - 23 Feb 2012

Vinardell Tatiana, Rolfe Rebecca A, Buckley Conor T, Meyer Eric G, Ahearne Mark, Murphy Paula, Kelly Daniel J

Abstract excerpt

Hydrostatic pressure (HP) is a key component of the in vivo joint environment and has been shown to enhance chondrogenesis of stem cells. The objective of this study was to investigate the interaction between HP and TGF-β3 on both the initiation and maintenance of a chondrogenic phenotype for joint tissue derived stem cells. Pellets generated from porcine chondrocytes (CCs), synovial membrane derived stem cells...

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Identifiers

PMID: 22370795
DOI: 10.22203/ecm.v023a09

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