Article
TNF-alpha promoter polymorphisms in sudden infant death.
Human immunology - 1 Jun 2008
Ferrante Linda, Opdal Siri H, Vege Ashild, Rognum Torleiv O
Abstract excerpt
Several studies indicate that the immune system is stimulated in sudden infant death syndrome (SIDS). Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine that strongly affects the cytokine cascade. A genetic variant associated with high production of TNF-alpha may thus be of significance in the pathogenesis of SIDS. The purpose of the current study was to investigate possible relationships among...
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