Article
Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis.
Hepatology (Baltimore, Md.) - 1 Jul 2008
Piodi Aurélie, Chouteau Philippe, Lerat Hervé, Hézode Christophe, Pawlotsky Jean-Michel
Abstract excerpt
UNLABELLED: Hepatocellular steatosis is common in patients with chronic hepatitis C. Steatosis can be considered as a true cytopathic lesion induced by hepatitis C virus (HCV) genotype 3, suggesting that one or more viral proteins produced during genotype 3 infection are involved in the steatogenic process, while the same proteins produced during infection by other genotypes are not. We examined in vitro...
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